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Cell Therapeutics

About Cell Therapeutics:

About Cell Therapeutics Cell Therapeutics, Inc. (CTI) is a biopharmaceutical company with a diversified portfolio of proprietary oncology drugs. Using genomic information to develop a personalized approach to cancer therapy, the company's goal is to make standard-of-care treatment less toxic and more effective for individual patients.

CTI is focused on gaining approvals for its two phase III product candidates, pixantrone in relapsed aggressive non-Hodgkin's lymphoma (NHL), and OPAXIO in ovarian cancer. Pixantrone is a novel compound designed to improve efficacy and safety treating cancers normally treated with anthracyclines. Based on the EXTEND (PIX301) phase III clinical trial which achieved its primary efficacy endpoint, CTI submitted an NDA to the FDA in June 2009 for pixantrone use in the treatment of relapsed or refractory aggressive non-Hodgkin's lymphoma (NHL). Pixantrone has fast track status for the relapsed / refractory aggressive NHL application. OPAXIO(tm) (paclitaxel poliglumex) is a biologically enhanced chemotherapeutic that links paclitaxel to a biodegradable polyglutamate polymer. It is in pivotal trials for ovarian and non-small cell lung (NSCLC) cancers.

Another product is in phase II clinical development. Brostallicin is a unique minor groove binding agent being studied in advanced or metastatic soft tissue sarcoma and myxoid liposarcoma.

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