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Hollis-Eden Pharmaceuticals

About Hollis-Eden

Hollis-Eden is focused on a class of hormones and analogs of hormones found in the body that it believes are important components of the body's regulatory system. These compounds appear to reduce inflammation in a broad–spectrum fashion while also improving a number of components of the immune system in conditions of immune suppression. .

 

Pipeline for Hollis-Eden

 

Hollis-Eden currently has three drug candidates in advanced development:

HE2100 NEUMUNE is being co-developed with the U.S. Department of Defense for use in protecting the body's bone marrow from acute radiation syndrome. The compound is being developed pursuant to a new rule enacted by the U.S. Food and Drug Administration (FDA) under which approval may be granted on the basis of demonstrating efficacy in animals and safety in humans.

PHOSPHONOL™ , a non-IRH compound, has the potential to protect against DNA mutations (mutagenesis) that are believed to be a primary cause of the harmful long-term effects of radiation injury associated with an increased risk of a variety of cancers.

With PHOSPHONOL and NEUMUNE™, Hollis-Eden could offer products to treat both the short and long-term effects of radiation injury.

(HE2000) IMMUNITIN Has shown activity in malaria and HIV. Given its anti-inflammatory and anti-infective activities in clinical and preclinical studies, IMMUNITIN has been selected by the Cystic Fibrosis Foundation for a collabortive research study. In addition, the U.S. military is screening IMMUNITIN and other IRHs as countermeasures against a number of pathogens that could be used as biowarfare agents.

 

 

 

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